Research

Research Publications

Peer-reviewed publications spanning neurotrauma, retinal and lens biology, regenerative medicine, biomedical optics, and neuropharmacology.

1. 2026

   Mesenchymal Stem Cell Secretome Attenuates Disease-Associated Microglial Activation and Cognitive Decline in TBI-Associated Neuroinflammation.

   Rasiah PK, Ismael S, Elshaer S, Awad AM, Salman M, Wang Z, Cho H, Bajpai AK, Liao FF, Lu L, Pentecost M, Ishrat T, Gangaraju R.

   Neurochem Int. 2026 Jun 24:106210.

2. Neuroglial response to high-amplitude, short-duration pressure transients in monoculture.

   Jenkins JL*, Rasiah PK*, Hardenburger J, Adams W, Mahadevan-Jansen A, Millis B, Jansen ED.

   Cell Biochemistry and Function, 2026. May;44(5):e70231 — * Shared first authorship

3. 2025

   Neurotrauma induced retinal basement membrane COL4A1 defects are restored by adipose tissue derived mesenchymal stem cell concentrated conditioned medium.

   Rasiah PK, Jha KA, Gentry J, Del Mar NA, Pfeffer LM, Reiner A, Gangaraju R.

   Stem Cell Res Ther. 2025 Dec 15;16(1):677.

4. Handheld Laser Speckle Contrast Imaging Probe: Quantitative Video-rate Assessment of Tissue Perfusion in Animal and Patient Applications.

   Han Dong, Parker Willmon, Rasiah PK, Sean Fitzgerald, Emmanuel Mannoh, Carmen Solórzano, and Anita Mahadevan-Jansen.

   Biophotonics Discovery 2025. Vol. 2, Issue 3, 035003.

5. Infrared Neural Stimulation Elicits Distinct Molecular Pathways in Astrocytes Based on Laser Pulse Parameters.

   Adams WR, Borrachero-Conejo AI, Rasiah PK, Saracino E, Zamboni R, Jansen ED, Benfenati V, Mahadevan-Jansen A.

   Adv Biol (Weinh). 2025 Aug 21:e00269.

6. Subcellular and macrostructural immediate responders to airblast traumatic brain injury.

   Rasiah PK, Hardenburger J, Dong H, Hardin R, Locke A, Jenkins JL, Artis E, Caskey C, Millis B, Jansen ED, Rex TS, Mahadevan-Jansen A.

   Sci Rep. 2025 Aug 4;15(1):28454.

7. Biochemical detection of pediatric eosinophilic esophagitis using high-wavenumber Raman endoscopy and stimulated Raman microscopy.

   Haugen EJ, Locke AK, Dao LH, Walter AB, Rasiah PK, Baba JS, Buendia MA, Correa H, Hiremath G, Mahadevan-Jansen A.

   Sci Rep 15, 2025. 22471.

8. TNF-Stimulated Gene-6, Part of Extracellular Vesicles in Adipose Tissue-Derived Mesenchymal Stem Cell Concentrated Conditioned Medium, Affects Microglial Activity.

   Hossain MS, Rasiah PK, Seetharaman ATM, Alvarado D, Luo M, Wohlschlegel JA, Pentecost M, Gangaraju R.

   J Neuroimmune Pharmacol. 2025 May 29;20(1):60.

9. 2024

   Ultrasound Modulates Calcium Activity in Cultured Neurons, Glial Cells, Endothelial Cells and Pericytes.

   Newman M, Rasiah PK, Kusunose J, Rex TS, Mahadevan-Jansen A, Hardenburger J, Jansen ED, Millis B, Caskey CF.

   Ultrasound Med Biol. 2024 Mar;50(3):341-351

10. 2023

    Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium.

    Soucy JR, Aguzzi EA, Cho J, Gilhooley MJ, Keuthan C, Luo Z, Monavarfeshani A, Saleem MA, Wang XW, Wohlschlegel J; RReSTORe Consortium; Baranov P, Di Polo A, Fortune B, Gokoffski KK, Goldberg JL, Guido W, Kolodkin AL, Mason CA, Ou Y, Reh TA, Ross AG, Samuels BC, Welsbie D, Zack DJ, Johnson TV.

    Mol Neurodegener. 2023 Sep 21;18(1):64.

11. Enhanced characterization of breast cancer phenotypes using Raman micro-spectroscopy on stainless steel substrate.

    Thomas G, Fitzgerald ST, Gautam R, Chen F, Haugen E, Rasiah PK, Adams WR, Mahadevan-Jansen A.

    Anal Methods. 2023 Mar 2;15(9):1188-1205.

12. 2022

    A Long-Term Safety and Efficacy Report on Intravitreal Delivery of Adipose Stem Cells and Secretome on Visual Deficits After Traumatic Brain Injury.

    Rasiah PK, Jha KA, Gentry J, Del Mar NA, Townsend T, Torgbe KE, Reiner A, Gangaraju R.

    Transl Vis Sci Technol. 2022 Oct 3;11(10):1.

13. Mesenchymal stem cell secretome protects against oxidative stress-induced ocular blast visual pathologies.

    Jha KA, Rasiah PK, Gentry J, Del Mar NA, Kumar R, Adebiyi A, Reiner A, Gangaraju R.

    Exp Eye Res. 2022 Feb;215:108930.

14. 2021

    Mesenchymal Stem Cell Induced Foxp3(+) Tregs Suppress Effector T Cells and Protect against Retinal Ischemic Injury.

    Agrawal M, Rasiah PK, Bajwa A, Rajasingh J, Gangaraju R.

    Cells. 2021 Nov 4;10(11):3006.

15. Visual deficits after traumatic brain injury.

    Rasiah PK, Geier B, Jha KA, Gangaraju R.

    Histol Histopathol. 2021 Feb 18:18315.

16. 2019

    Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.

    Rasiah PK, Maddala R, Bennett V, Rao PV.

    Dev Biol. 2019 Feb 1;446(1):119-131.

17. 2015

    Real-time heterogeneous protein-protein interaction between αA-crystallin N-terminal mutants and αB-crystallin using quartz crystal microbalance (QCM).

    Ramkumar S, Fujii N, Sakaue H, Fujii N, Thankappan B, Rasiah PK, Natarajaseenivasan K, Anbarasu K.

    Amino Acids. 2015 May;47(5):1035-43.

18. Transcriptional regulation of crystallin, redox, and apoptotic genes by C-Phycocyanin in the selenite-induced cataractogenic rat model.

    Rasiah PK, Ramkumar S, Thankappan B, Natarajaseenivasan K, Balaji S, Anbarasu K.

    Mol Vis. 2015;21:26-39.

19. Etiology and Prevention of Cataract.

    Rasiah PK, Ramkumar S, Thankappan B, Anbarasu K.

    In: Studies on the Cornea and Lens. Oxidative Stress in Applied Basic Research and Clinical Practice. Humana Press, New York, NY. — Book chapter

20. 2014

    Protective role of C-phycocyanin against secondary changes during sodium selenite mediated cataractogenesis.

    Rasiah PK, Anbarasu K.

    Nat Prod Bioprospect. 2014 Apr;4(2):81-9.

21. 2013

    C-phycocyanin modulates selenite-induced cataractogenesis in rats.

    Rasiah PK, Sivakumar J, Thankappan B, Anbarasu K.

    Biol Trace Elem Res. 2013 Jan;151(1):59-67.

22. 2012

    Polychlorinated biphenyl (PCBs)-induced oxidative stress plays a critical role on cerebellar dopaminergic receptor expression: ameliorative role of quercetin.

    Bavithra S, Selvakumar K, Rasiah PK, Krishnamoorthy G, Venkataraman P, Arunakaran J.

    Neurotox Res. 2012 Feb;21(2):149-59.

23. 2011

    Role of quercetin on PCBs (Aroclor-1254) induced impairment of dopaminergic receptor mRNA expression in cerebral cortex of adult male rats.

    Rasiah PK, Selvakumar K, Bavithra S, Zumaana R, Krishnamoorthy G, Arunakaran J.

    Neurochem Res. 2011 Aug;36(8):1344-52.